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The Ontario County Public Health Department is investigating a suspected hantavirus case in upstate New York. Officials emphasized the case has no connection to the MV Hondius cruise ship outbreak, which has identified 11 cases (8 confirmed, 2 probable, 1 inconclusive) with 3 deaths. The cruise outbreak involves the Andes virus strain, which is noted as one of the rare hantavirus strains capable of human-to-human transmission. Hantavirus infections in New York remain uncommon and are primarily transmitted through rodent droppings. Public health authorities recommend protective measures—gloves and masks—when cleaning enclosed spaces where rodents may be present, including attics, cabins, sheds, and garages.